Technical guide

Drug Loading on Mineral Carriers: Close the Mass Balance

A loading percentage is useful only when its denominator and analytical recovery are defined. This guide separates feed depletion from drug measured on the recovered carrier and sets out the controls needed for an interpretable development comparison.

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How to use it

Use the two-page PDF to structure a development review and identify the evidence still needed for your material, process and intended use. Keep the method, sample identity and reporting basis with each result.

Technical review pending. This educational draft is not a product specification, batch COA, validated test method, regulatory approval or finished-device performance claim. Confirm application-specific requirements before making a qualification decision.

Key checks in the PDF

  • Keep the same analyte basis across the feed, wash liquids and recovered carrier, and record whether the product was washed.
  • Report loading efficiency and drug loading with their denominators rather than treating the percentages as interchangeable.
  • Account for mother liquor, washes, apparatus recovery and recovered-solid drug before interpreting the unaccounted fraction.

Relevant material pages

These links provide material context, not evidence of validated drug loading or finished-device performance.

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